Using our proprietary bioactive hydrogels, we construct tumor organoids: 3D cellular structures made from cancerous cells. These structures allow for more natural cell-to-cell signaling and growth than can be achieved in traditional 2D cell cultures or in animal xenograft models.

To demonstrate the promise of our platform we will validate our tumor models against previous clinical results using a retroactive, blinded study where we will show our ability to replicate clinical data within our system - stepping away from guesswork and towards reproducible successes. 

The microenvironment is what surrounds and supports our cells, and helps provide structure to the various tissues that make up our bodies. The physical and chemical aspects and components of a tumor's microenvironment are critical for directing how the tumor grows and spreads in the body. By replicating the tumor microenvironment, TissueTinker provides a more realistic representation of tumors as they appear in the body.

Our models are agnostic of the original cell source, and can be readily used with both patient cells and immortalized cell lines. This allows us to further democratize healthcare by testing new therapeutics on cells from patients of a variety of different backgrounds and health states.